Can Baclofen Cause Heart Problems? | Does Baclofen Work?

Baclofen oral tablet is a drug that’s only available in a generic form. There is no brand name available for this drug.

Baclofen also comes as a spinal injection, and only healthcare providers can give it.

Why is it used?

Baclofen is a muscle relaxer used to heal muscle pain, spasms, and stiffness in people with multiple spinal cord injuries or diseases.

Baclofen is commonly used to reduce spasticity and is associated with increased quality of life in spinal cord patients. Appropriate doses of oral Baclofen are low and generally well-tolerated, but overdose can lead to severe spasticity.

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How does it work?

Baclofen is a drug called a muscle relaxer. A drug is a group of medications that work similarly. Baclofen is known for its ability to treat complicated situations of muscle pain.

Baclofen blocks the signs of a nervous system that helps prevent your muscles pain.

How long does baclofen take to work?

According to some researchers, some people reported a reduction in muscle spasm symptoms within a few hours after taking Baclofen. Indifference, for some others, Baclofen may take several weeks to reduce the symptoms of muscle spasms.

Can baclofen cause heart problems?

Cardiovascular side effects of Baclofen are the most reported side effect after taking an overdose. In addition, hemodynamic changes and conduction abnormalities, including first-degree heart block, premature atrial contractions, and supraventricular tachycardia, have been claimed in some cases after taking Baclofen overdoes.

According to the research, In rare cases, the patient showed a severe heart conduction problem after a high dosage of Baclofen.

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What should I discuss with the doctor before taking baclofen?

You should not take Baclofen if you are allergic to it.

Notify your doctor if you ever had the following:

  • Mental illness 
  • A nervous system disorder
  • Epilepsy or other seizure disorder
  • A stroke or blood clot
  • Kidney disease.

Taking Baclofen may increase your risk of developing an ovarian cyst. Speak with your doctor about your specific risk.

Must tell your doctor or healthcare provider if you are pregnant or breastfeeding.

If you use Baclofen during pregnancy, your newborn baby may suffer from several problems such as tremors, stiff muscles, or a seizure. Follow your doctor’s instructions about your dosage during pregnancy.

If you take Baclofen while breastfeeding, several symptoms may occur in the nursing baby. Confirm with your doctor that it is reliable for you to breastfeed while taking Baclofen.

Baclofen is not recommended for anyone younger than 12 years old.

What should I avoid while taking baclofen?

Do not use Baclofen when you need a balanced muscle tone for daily activities because it can be critical to reducing muscle tone.

Consuming alcohol with this medication can cause side effects.

Avoid driving or hazardous activity while you are on this medication. 

Possible side effects

Get emergency help if you have symptoms of an allergic reaction such as hives, difficult breathing, swelling on your face, tongue, throat, or lips.

Call your doctor on an emergency basis in the following situations:

  • Severe drowsiness, weakness, or shallow breathing
  • Confusion
  • Itching or twitching in your hands, arms, legs, or feet
  • Fever
  • A seizure

Other common side effects may include:

  • Drowsiness, dizziness, weakness, tiredness
  • Headache
  • Sleeping problems (insomnia)
  • Nausea and constipation
  • Urinating more often than usual

Warnings for people with specific health conditions

EpilepsyTalk to your doctor about this drug is safe for you. 

Kidney problems: If you have kidney problems, you may not be correctly clear this drug from your body. It may increase the levels of baclofen in your body and produce a more severe side effect. 

If you have kidney disease, your doctor takes you at a lower dose.

Stroke: If you’ve had a stroke, you may have more severe side effects with baclofen. This drug may also not work for muscle pain.

Pregnant women: It isn’t baclofen that is safe for use in pregnant women. Discuss with your doctor if you’re pregnant or plan to become pregnant.

Breastfeeding: It isn’t known if baclofen passes into breast milk. It may cause side effects in a baby who is breastfeeding. 

Children: baclofen hasn’t been studied and shouldn’t be used in children over 12 years.

How to stop taking baclofen?

Don’t stop taking this medication without asking your doctor. Stopping it suddenly can cause seizures and hallucinations. If you want to stop taking this drug, your doctor will slowly lower your dosage over time.

If you stop taking this medication suddenly or don’t take it at all: Your muscle spasms may get worse.

If you avoid doses or don’t take them regularly, your medication may not work as well or may stop working altogether. For this drug to work correctly, you need to take this medication appropriately.

Frequently Asked Question

Does baclofen reduce appetite?

According to research, the results of animal studies suggest that baclofen can reduce the appetite for certain palatable and high-calorie foods. Energy-dense carbohydrates and fats are largely responsible for the increasing incidence of obesity worldwide.

When is the best time to take baclofen?

Try to take your dose at the same time each day or take baclofen with breakfast or after a meal. Taking baclofen at one time will help you remember to take it. If you forget to take a dose, skip the missed dose and remember to take the next dose when it is due.

What does baclofen do to the brain?

GABA (Baclofen is a chlorophenyl derivative of gamma-aminobutyric acid) , a naturally occurring inhibitory neurotransmitter in the brain and spinal cord.

It has proven therapeutic value in reducing the severity of flexor or extensor spasm resulting from spinal cord injury or disease.

What are the risks of baclofen?

Side effects of baclofen such as depression, confusion, mood or mental changes, severe drowsiness are seen especially in elderly patients. Who are generally more sensitive to the effects of this drug than younger adults.


Your doctor will likely monitor specific health issues. This can help to ensure that you stay safe while taking this drug.

If you want to stop taking this drug, there are other drugs available to treat your condition. Some can suit you better than others. Consult with your doctor about other options that may work for you.

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