Tramadol is a controlled substance that contains an opioid.

Tramadol is a pain medicine that can help with moderate pain. It has side effects, nausea, however, dizziness, sweating. Less common side effects include hives and confusion.

Tramadol has to be taken orally and is available in three forms – an immediate-release tablet, extended-release tablet, and capsule. In addition, this medicine can be taken as a combination therapy, where you take it with other medicines for your treatment.

Doctors prescribe tramadol to people over 12 years old. Teenagers with risk factors should speak with doctors about the risks of taking tramadol.

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This article discusses the side effects of tramadol. We will also take a look at tramadol dependence.

What is Tramadol?

Ultram and Ultram ER are the brand names of the drug tramadol. They are available in the form of direct and extended-release tablets. In addition, tramadol is combined with acetaminophen in the drug Ultracet.

The table lists the dosages of tramadol in milligrams (mg).

Brand name	Active ingredient and dosage	Type of release
Ultram	tramadol 50 mg	immediate release
Ultram ER	tramadol 100 mg tramadol 200 mg tramadol 300 mg	extended release
Ultracet	acetaminophen 325 mg tramadol 37.5 mg	immediate release

Doctors should choose the lowest dosage for the shortest period and train people on the risks of taking tramadol.

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Side effects

Tramadol causes side effects in some people. They occur when people start taking tramadol and can wear off over time.

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Some common side effect

Dizziness and vertigo
Drowsiness
Itchiness
Weakness
Dry mouth
Diarrhea
Nausea
Vomiting
Constipation
Headache

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Less common side effects

People experience other side effects that occur with an incidence of less than 5%.

Whole body discomfort
Weight loss
Hives
Rash
Fainting
Rapid heartbeat
Allergic reactions
Suicidal tendencies

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Drug interactions

Tramadol interacts with medications, such as benzodiazepines and serotonergic drugs.

Benzodiazepines

Benzodiazepines are drugs that reduce anxiety. People use them to treat insomnia and anxiety.

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If someone takes benzodiazepine medication such as lorazepam or alprazolam, taking tramadol can result in sedation, depression, coma, and death.

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Serotonergic drugs

Serotonergic drugs affect serotonin levels in your body. People use them to treat depression.

People who are taking serotonergic drugs should use tramadol carefully.

Drug class	Drugs
selective serotonin reuptake inhibitors (SSRIs)	citalopram, escitalopram, fluvoxamine, paroxetine, sertraline
serotonin and norepinephrine reuptake inhibitors (SNRIs)	venlafaxine, duloxetine, desvenlafaxine
tricyclic antidepressants	amitriptyline, imipramine, clomipramine
triptans	almotriptan, rizatriptan, sumatriptan
5-HT3 receptor antagonists	granisetron, ondansetron
monoamine oxidase inhibitors (MOIs)	phenelzine, selegiline

Does tramadol have aspirin or tylenol in it?

It contains two medicines: tramadol and acetaminophen. It is similar to opioid analgesics.

It works in the human brain to change how the body feels and responds to pain. For example, acetaminophen is used to reduce pain, and it can reduce a fever.

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When to see a doctor

People who are taking tramadol report side effects to their doctor. By discussing the benefits or risks of the medication, a doctor can help a person find the appropriate medicine at the lowest effective dosage.

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Anyone having trouble breathing or experiencing symptoms of serotonin syndrome seek immediate medical care.

Conclusion

Tramadol is an opioid pain medicine. It acts on brain chemicals called serotonin and norepinephrine to reduce moderate pain.

Tramadol is not safe for everyone. Children under 12 years do not take tramadol, and those aged 12–18 use caution when taking it.

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Is Tramadol A Controlled Drug? | Does Tramadol Have Aspirin?

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