Is Tramadol A Controlled Drug? | Does Tramadol Have Aspirin?

Tramadol is a controlled substance that contains an opioid.

Tramadol is a pain medicine that can help with moderate pain. It has side effects, nausea, however, dizziness, sweating. Less common side effects include hives and confusion.

Tramadol has to be taken orally and is available in three forms – an immediate-release tablet, extended-release tablet, and capsule. In addition, this medicine can be taken as a combination therapy, where you take it with other medicines for your treatment.

Doctors prescribe tramadol to people over 12 years old. Teenagers with risk factors should speak with doctors about the risks of taking tramadol.

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This article discusses the side effects of tramadol. We will also take a look at tramadol dependence.

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Table of Contents

What is Tramadol?

Ultram and Ultram ER are the brand names of the drug tramadol. They are available in the form of direct and extended-release tablets. In addition, tramadol is combined with acetaminophen in the drug Ultracet.

The table lists the dosages of tramadol in milligrams (mg).

Brand nameActive ingredient and dosageType of release
Ultramtramadol 50 mgimmediate release
Ultram ERtramadol 100 mg
tramadol 200 mg
tramadol 300 mg
extended release
Ultracetacetaminophen 325 mg
tramadol 37.5 mg
immediate release

Doctors should choose the lowest dosage for the shortest period and train people on the risks of taking tramadol.

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Side effects

Tramadol causes side effects in some people. They occur when people start taking tramadol and can wear off over time.

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Some common side effect

  • Dizziness and vertigo
  • Drowsiness
  • Itchiness
  • Weakness
  • Dry mouth
  • Diarrhea
  • Nausea
  • Vomiting
  • Constipation
  • Headache

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Less common side effects

People experience other side effects that occur with an incidence of less than 5%.

  • Whole body discomfort
  • Weight loss
  • Hives
  • Rash
  • Fainting
  • Rapid heartbeat
  • Allergic reactions
  • Suicidal tendencies

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Drug interactions

Tramadol interacts with medications, such as benzodiazepines and serotonergic drugs.


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If someone takes benzodiazepine medication such as lorazepam or alprazolam, taking tramadol can result in sedation, depression, coma, and death.

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Serotonergic drugs

Serotonergic drugs affect serotonin levels in your body. People use them to treat depression.

People who are taking serotonergic drugs should use tramadol carefully.

Drug classDrugs
selective serotonin reuptake inhibitors (SSRIs)citalopram, escitalopram, fluvoxamine, paroxetine, sertraline
serotonin and norepinephrine reuptake inhibitors (SNRIs)venlafaxine, duloxetine, desvenlafaxine
tricyclic antidepressantsamitriptyline, imipramine, clomipramine
triptansalmotriptan, rizatriptan, sumatriptan
5-HT3 receptor antagonistsgranisetron, ondansetron
monoamine oxidase inhibitors (MOIs)phenelzine, selegiline

Does tramadol have aspirin or tylenol in it?

It contains two medicines: tramadol and acetaminophen. It is similar to opioid analgesics.

It works in the human brain to change how the body feels and responds to pain. For example, acetaminophen is used to reduce pain, and it can reduce a fever.

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When to see a doctor

People who are taking tramadol report side effects to their doctor. By discussing the benefits or risks of the medication, a doctor can help a person find the appropriate medicine at the lowest effective dosage.

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Anyone having trouble breathing or experiencing symptoms of serotonin syndrome seek immediate medical care.


Tramadol is an opioid pain medicine. It acts on brain chemicals called serotonin and norepinephrine to reduce moderate pain.

Tramadol is not safe for everyone. Children under 12 years do not take tramadol, and those aged 12–18 use caution when taking it.


Let me know if you know any other tips that allow you to treat yourself the fastest way possible.

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