What Does Sucralfate Do?

What does sucralfate do? 

Sucralfate is used to treat and prevent ulcers in the intestines. In addition, sucralfate forms a coating over ulcers, protecting the area from further injury. This helps ulcers heal quickly.

I had earlier shared Stomach Ulcer Extreme Fatigue? I hope you read.

What Symptoms Does Sucralfate Help?
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Table of Contents

How to use sucralfate oral?

Take this medicine by your mouth, 2 to 4 times every day, on an empty stomach 1 hour before your meal or as directed by the doctor. The dosage of this medicine is based on your medical condition.

Use this medication daily to get the benefit from it. Use it at the same time every day. Keep taking this medicine even if you do not feel ulcer pain. Don’t stop taking this medication without consulting the doctor. It takes 4 to 8 weeks for your ulcer to heal perfectly.

Antacids can also be used with this medicine but should take 30 minutes before or after sucralfate.

If your condition persists or worsens after taking sucralfate for four weeks, inform your doctor first.

Side effects

Constipation, gas, upset stomach, dry mouth, and nausea may occur. If these effects worsen, tell your doctor or pharmacist immediately.

Remember that your doctor or physician has prescribed this medication because they have found that your benefit is higher than your risk of side effects. Many people using this medicine do not have severe side effects.

Tell your doctor if you have serious side effects, including an unusual/persistent feeling of fullness in the stomach, stomach pain, nausea, vomiting, especially after meals, trouble swallowing.

I also wrote a tutorial Acidity Pain In Stomach on you can read this post.

I recommend IBgard Daily Gut Health Support to take relief from stomach cramps. It is clinically shown to promote abdominal comfort, including a combination of symptoms of cramping, diarrhea, constipation, bloating, and gas.



Before taking the sucralfate pill, tell your doctor if you are allergic to it or have some other allergies. This product contains inactive ingredients, which cause allergic reactions or other problems. Talk to your pharmacologist for more details.

Before using this sucralfate, tell your doctor your medical history, especially of: kidney problems, swallowing problems, stomach/intestine problems, tube feeding, and a breathing tube.

If you are pregnant, tell the doctor before using sucralfate.

It is not yet known whether sucralfate passes into breast milk. Therefore, consult a doctor before breastfeeding.

You must read this article Best Homeopathic Medicine For Stomach Problems

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Drug interactions may increase your risk for severe side effects. This document does not contain all medication interactions. Make one list of all products you use and share it with the doctor and druggist. Do not start or stop the drug dosage without the doctor’s approval.

Some products that may also interact with this drug include antacids that contain aluminum, penicillamine, certain antibiotics, ketoconazole, quinidine, digoxin, phenytoin, thyroid medications.

Sucralfate dosing information

Usual Adult Dose for Duodenal Ulcer:

Oral Tablets: 1 g orally four times a day

Duration: 4 to 8 weeks

Comments: Should take every dose on an empty stomach.

-For some patients, treatment should continue for 4 to 8 weeks; however, they can stop treatment early if healing is demonstrated on x-ray/endoscopic tests.

-Antacids may be given, but different use by 30 minutes.

Use: Short-term treatment of active duodenal ulcers.

Usual Adult Dose for Duodenal Ulcer Prophylaxis:

Oral Tablets: 1 g two times a day

Duration: Up to 1 year

Comments: Each dose is taken on an empty stomach.

Use: Maintenance therapy for patients after healing of severe duodenal ulcers.


Your doctor recommends some lifestyle changes such as stress-reducing programs, diet changes, and exercise to help in treating and preventing ulcers.

Do not share this medicine with others.

Missed dose

If you miss the daily dose, take it as soon as possible. However, if it is near the time of your next dose, you can skip the missed dose. Instead, take the next dose at your regular time.

Frequently Asked Question

How long does it take sucralfate to work?

It may take up to eight weeks before an ulcer is fully healed. Each 1g dose of sucralfate neutralizes about 14 to 16 mEq of stomach acid.

Does sucralfate help acid reflux?

Sucralfate is effective for the treatment of human reflux oesophagitis1,2,3,4; however, recent first-line treatments for gastroesophageal reflux disease are proton pump inhibitors which control gastric acid secretion.

What is the most common side effect of sucralfate?

Constipation. The most common side effect of sucralfate is constipation. The medication works by binding to ulcers to protect them from further exposure to stomach acid, bile, pepsin, and bile salts. This gives the ulcers time to heal.

What happens if you take sucralfate with food?

Stomach and bowel disease—Sucralfate may bind with other meals and drugs which may cause blockage of the stomach and bowels.

Does sucralfate heal gastritis?

Abstract. Sucralfate is a cytoprotective drug widely used in clinical practice to control or treat several gastrointestinal diseases such as gastroesophageal reflux, gastritis, peptic ulcer, stress ulcer, and dyspepsia.


Store at room temperature away from moisture and light. Do not store in the toilet. Keep all these medications away from children and pets.

Don’t flush medicines down the toilet or empty them into a drain unless instructed. Correctly discard this product when no longer needed. Consult with your pharmacist or local waste disposal company.

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